Those attempting to foil the drug screen process may try to add certain enzymes to the urine sample to affect stability, but this often changes the pH, which is also tested. The most common adulterants used include certain oxidizing agents – such as nitrites, glutaraldehyde, chromates and halogens like bleach and iodine.
To join others who may have questions, concerns or want to voice opinions about illicit and prescription drug testing, false positives, false negatives, and other related issues, visit:
A low creatinine lab value can indicate that a urine sample was tampered with – either the subject diluted their urine by consuming excessive water just prior to testing, or water was added to the urine sample. Creatinine levels are often used in conjunction with specific gravity to determine if samples have been diluted.
More News Resources
Even though these tests are common, people often have questions about the possibility of false-positive results. Anyone subject to a drug screen should confirm that secondary confirmatory testing (such as gas chromatography–mass spectrometry [GC-MS] or high performance liquid chromatography) is performed on any positive result received by the lab doing your testing. 1
Have you been asked to take a drug test? Maybe this caught you off guard. Screening drug tests are often required for pre-employment in the private and government sector, for athletes, students, healthcare workers, for probation or criminal activity, for opioid avoidance testing in the clinic, or after vehicle or workplace accidents. Random drug testing can also occur at any time at a workplace, during an employee physical exam, and for any reasonable suspicion of drug use.
To help avoid this problem, the testing lab may color the water in their toilet to prevent the sample from being diluted with toilet water. The temperature of urine is also measured, to help prevent use of a substituted urine sample brought in from the outside.
With the 300 ng/mL cutoff for urine testing, morphine was detected after rolls in 50 percent of samples at 20 hours, and in 100 percent of raw poppy seeds after 20 hours. With oral fluid testing, morphine fell below the 30 ng/mL detection limit with rolls after 30 minutes and from raw seeds at one hour.
USADA cannot predict the amount of poppy seeds you can eat and remain below the testing threshold set by WADA. **In most cases, consumption of poppy seeds in foods will not cause a positive doping test.
Research shows that morphine and codeine can sometimes be detected in the urine up to 48 hours after ingestion of poppy seeds from some pastries, such as bagels, muffins, and cakes (see reference one for a free article on this topic).
Can the morphine from poppy seeds be detected in a sample?
However, it may be possible to exceed the morphine threshold by eating foods with poppy seeds and USADA can’t predict how long morphine or morphine metabolites from poppy seeds will stay in your system. The most conservative approach would be to avoid poppy seeds a few days before and during competitions.
Lachenmeier DW, Sproll C, Musshoff F. Poppy seed foods and opiate drug testing—where are we today? Ther Drug Monitor. 2010 Feb; 32(1): 11-18.
Thevis M, Opfermann G, Schänzer W. Urinary Concentrations of Morphine and Codeine After Consumption of Poppy Seeds. J Anal Toxicol (January-February 2003) 27(1): 53-56 . URL: http://www.ncbi.nlm.nih.gov/pubmed?term=morphine%20and%20codeine%20on%20poppy%20seeds%20thevis
The opium is composed of roughly 12 percent morphine, which is a narcotic that is prohibited in-competition. According to the World Anti-Doping Agency (WADA) Prohibited List, morphine is a threshold substance, meaning that WADA-accredited laboratories determine if a sample is positive for morphine when the level of morphine in the urine is greater than *1.3 micrograms/mL.
Massachusetts Medical Society: “Urine Abstinence Testing And Incidental Alcohol Exposure.”
This beverage is a popular folk remedy in Peru and elsewhere in South America. It’s made with the leaves of the same plant that cocaine comes from. If you drink it, you may want to stop a couple of days before your drug test. Coca tea could affect your screening for up to 36 hours after you’ve sipped it.
Operation Supplement Safety: “Weight-Loss Prescription Drugs: Phentermine.”
National Institute on Drug Abuse for Teens: “What is Hemp?”
U.S. National Library of Medicine: “Drug Testing,” “Quinine,” “Diphenhydramine,” “Dextromethorphan,” “Efavirenz,” “Amphetamine,” “Sertraline.”
Quest Diagnostics Employer Solutions Blog: “Cannabidiol and drug tests.”
Efavirenz (Sustiva) is an antiretroviral drug that helps treat your HIV infection. But on a drug screen, it can make you seem to have used marijuana. A second, more sensitive test should be able to distinguish which of the two compounds is in your body. To avoid confusion, you may want to alert the lab or the clinic beforehand that you’re on efavirenz.