CBD Oil Users


Buy CBD Oil Online

Most Effective Royal Cbd Oil Users Group | Sandy Beach Hotel Hemp Oil Vs Cbd Oil royal cbd oil users group Help People Relieve Pain, royal cbd oil and dementia. The ghost knows what kind of CBD has been touted to help with sleep, anxiety, pain, and more, and there are myriad ways to take it. But does CBD work? Is it safe? We’ve got answers.

Most Effective Royal Cbd Oil Users Group | Sandy Beach Hotel

Hemp Oil Vs Cbd Oil royal cbd oil users group Help People Relieve Pain, royal cbd oil and dementia.

The ghost knows what kind of eyes Qin Shaoyou has Cbd Missouri royal cbd oil and dementia given birth to, and he can even see whether he is telling the truth or a lie at a glance.

What royal cbd oil users group kind of recipe is this It s clearly an encyclopedia of cooking ghosts If Best Cbd Brand royal cbd oil users group this situation continues, maybe sometime, tranquility labs the royal cbd oil users group royal cbd oil and dementia Online Sale cultivation method of food ingredients will royal cbd oil users group be given.

Cui Youkui, who had finished the silly fun, asked Ye Zhiqiu and the others about their intentions.

At the same time, Qin Shaoyou also activated the three Sandy Beach Hotel royal cbd oil users group talents of Bright Eyes , Debate royal cbd oil users group Listening and Miao Nose.

However, after Zheng Tu stuffed a piece of royal cbd oil users group silver ingot, the believer of the Black Lotus Sect finally revealed some news, saying that the little boy he strong cbd oil cheap was looking for was the leader of the Black Lotus Sect, winged gummies cbd the Best Cbd Brand royal cbd oil users group person whom Maitreya Buddha named royal cbd oil users group in the future.

This mouse is the rat king turned demon in the Abandoned Baby Tower.

I can cbd oil help a torn meniscus couldn t help muttering in my heart It s royal cbd oil users group okay to grab people s heads, and even royal cbd oil and dementia Online Sale to save people, you have to grab me Cui Youkui did not pay any attention to the swarms of poisonous insects whistling, as benefits of cbd cream well as Cbd Missouri royal cbd oil and dementia the sharp poisonous vines and tree roots.

Just a few words. Just now when he saw people come to ask about the situation, Senior Brother Cui held his head high and got ready, just waiting for cbd gummies dont work someone to ask him, so he can boast and let these people know what is the light american shaman cbd oil discount gummy bear cd walmart of the Jade nature made extended release melatonin reviews Emperor.

Their mood Benefits Of Cbd Oil royal cbd oil users group was both happy and moved. At first, they were a little cautious.

In fact, Cui Youkui knew this very well, but he just wanted to vent the anger in axis labs cbd oil review his heart.

The demons cbd oil ratio best for heart disease in the county town have basically been brought under control.

This is the Buddha statue of the Black Lotus Sect That Zheng Tu is really a monster of the Black Lotus Sect Qin Shaoyou looked solemn.

Hearing Wu Bufan s order, he do you need a medical card to get cbd oil immediately responded OK , pulled out his saber, jumped, and jumped to Wu Bufan s side.

Because he never thought that Qin Shaoyou would find here.

He could have let sun state hemp 1150 cbd gummies out his blood and swept away royal cbd oil users group the paper silver royal cbd oil users group ingot from Zhao Si s hand, but considering that the life buying Specter might have moved his hands and feet on the paper and silver ingot, he was afraid.

He now understands that these Qingji are indeed not stupid roe deer.

Immediately after the blood gas turned into fire, the shredded paper was burned into royal cbd oil users group ashes with a boom.

However, in the fantasy world, Zheng Tu did not is cbd oil legal to travel internationally react at all to the golden royal cbd oil users group needle that Qin Shaoyou took out.

Su Jianqing and Su Tingyu also agreed with Qin Shaoyou s arrangement.

People, don t give them this chance at all.

But it was too late. Although the royal cbd oil users group blood cloud in the sky only covered a few streets near the Demon Town, but the sunlight penetrated it royal cbd oil users group and covered everyone, making everyone feel as if they were covered in blood.

Not good The spider spirit turned pale with fright, and hurriedly wanted to agitate the demonic aura to get Sandy Beach Hotel royal cbd oil users group rid of this situation.

Not only did they not pull their companions off the candied haws, but they also stuck themselves with their companions.

They originally wanted to come up to greet them, but after walking a royal cbd oil users group few steps, they saw Zhu Xiucai wave his hand quietly, royal cbd oil users group and immediately understood royal cbd oil and dementia Online Sale that Qin Zongqi and the others were on a mission.

For the specific cooking method, Qin Shaoyou was not in a hurry to check it, and planned to wait until he was ready royal cbd oil users group to study it.

Watching the night watchman escort Zheng Tu and his associates to the torture chamber, Qin Shaoyou called Shan Daonian in front of him and whispered This Zheng Tu is probably a royal cbd oil users group hard nail, you should think royal cbd oil users group more about prying open his mouth.

But that kind of pain, that kind of royal cbd oil users group Cbd Manufacturing fear, is a more terrible torment than death In the past, Feng royal cbd oil users group Biao always felt that there was something wrong with the sentence that life is better than death.

In the meantime, quickly turn around and greet the team to follow.

Then he looked up at the night sky, the cbd oil bottle labels strange blood moon like a living creature, frowned and asked Xiusai, you have been in the Demon Suppression Division longer than me, and you have read more books than me, but you know this blood Best Cbd Brand royal cbd oil users group moon.

Soon, he touched the side of a demon. The demon was cursing in an odd, high pitched tone, unaware of Best Cbd Brand royal cbd oil users group Hong device to infuse cbd in gummies Cruise s arrival.

In order to prevent the people in Zhuangzi from running away after hearing the news of Wu Bufan s execution, Zhu Xiucai had to bring people over immediately to take over Zhuangzi and start a search.

He felt that Liu Shuyuan and Lao Zhangtou and Zhang royal cbd oil users group Xiaoni were probably separated on royal cbd oil users group Cbd Oil And Albuterol Side Effects purpose.

The miners did not respond, but the soldiers were in an uproar.

By the way, in Cai Guizhong s house, I also choose a few plots of land to send.

In fact, he wanted to urge them to quickly build Fei Fu gun.

The ancestor of Jiutian Dangmo has .

cbd oil henderson nv

been looking at the kitchen with the corner of his eye.

As Zhu Xiucai said before, when Cui Youkui sneaked into the State Town royal cbd oil users group Demon Division, he was indeed trapped by Ye Best Cbd Brand royal cbd oil users group Zhiqiu s replacement of the five elements, and then he was arrested Please enter the prison of the State Town Demon Division to experience life.

The intuition and appetite of Benefits Of Cbd Oil royal cbd oil users group the man who cooks make a difference But Qin Shaoyou, who was Best Cbd Brand royal cbd oil users group prime green royal cbd oil sober, couldn t care less about his luck, and even the expression on his face and the movements of his hands didn t change at all.

Qin Shaoyou looked up at the sky and greeted everyone Everyone, work hard, speed up your journey, and Best Cbd Brand royal cbd oil users group try to arrive at Changzhen before dark, and let Cai Lishi go home.

And if the Yin Soldier really hurts people, just closing the door and closing the window will not have a preventive effect at all.

But there is a man who is faster than him As early as when Senior royal cbd oil users group Brother Cui Cbd Missouri royal cbd oil and dementia took out the nine turn flying talisman, royal cbd oil users group Cbd Manufacturing Qin Sandy Beach Hotel royal cbd oil users group Shaoyou buckled a positive effects of oil fire escape talisman in his palm.

What s more, the blood cloud that covered the sky and the sun just now, and the blood rain that can make people crazy, were also witnessed and experienced by many people in the city.

Qin Shaoyou can be sure that Hong Gongliang and Best Cbd Brand royal cbd oil users group Niu Er did not lie.

Qin Shaoyou stopped. Nodding, he said solemnly Although Cai royal cbd oil users group Guizhong is dead, our Mianyuan County Town Demon royal cbd oil and dementia Online Sale Division is still there.

See also  CBD Essential Oil

He looked royal cbd oil and dementia Online Sale down and found royal cbd oil users group that he was no longer a flesh body, but a paper man Sun Laosan became the avatar he made And his body has long since disappeared.

No matter how he urged, no cbd oil 5 thc in kansas shipped to me matter how hard royal cbd oil and dementia Online Sale he poured into the jar of raising ghosts, it was of no use.

To hang him on an iron rack, cut his flesh one by one, and let him die in the midst of a pulse cbd gummies dosage thousand cuts Zheng Tu wanted to kill Qin Shaoyou, and Qin Shaoyou also wanted to kill him However, before Qin Shaoyou launched the charge, Zheng Tu launched the attack first.

This curse may not only take effect when they betray does weed candy get you high the Black Lotus Sect.

At this moment, his eyes suddenly widened. His eyes were actually bloodshot, and his entire face became hideous and crazy in an instant.

But just opened his mouth, before the royal cbd oil users group Cbd Manufacturing words were spoken, a dong dong dong drum sound suddenly sounded.

After speaking, Senior Brother Cui paused for a moment, then added Of course, the premise of these analyses, It s this bone that really belongs to Huang San.

He didn t embarrass Zhao Si royal cbd oil users group Cbd Manufacturing either. After laughing, he said, The evil spirits that bought your life have been eliminated, so you can go back in peace.

But they were in a very bad mood. Although Hong Yuyou knew about these demons, he royal blend cbd gummies 25mg was still a little scared when he saw them appearing in groups Cbd Missouri royal cbd oil and dementia and with resentment.

Old Zhangtou came from Mianyuan County royal cbd oil users group three years ago, and he brought this child So, could this child be the boy the Black Lotus Sect was looking for However, the aunt s answer was somewhat beyond Qin Shaoyou s expectations No, Lao Zhangtou was with a girl who was about five or six years old when he came.

But when dealing with baby ghosts, you can t just kill them with a single knife like you did with Wu Bufan.

According to the old lady, she and the royal cbd oil users group little boy are related to grandson and grandson.

Qin Shaoyou, who entered the lobby, put half of the boiled water black lotus on the offering table.

On the way, Hong Cruise did not complain less about Niu Er.

At this time, a night watchman was where to buy royal cbd oil in delaware already helping to push the coffin board royal cbd oil users group Cbd Manufacturing away.

Without saying a word, Qin Shaoyou immediately ran towards the lobby, and at royal cbd oil users group the same royal cbd oil users group Cbd Manufacturing time thought in his heart The ancestor royal cbd oil users group of Jiutian Dangmo is looking for me Cbd Missouri royal cbd oil and dementia at this time, is royal cbd oil users group Cbd Manufacturing it also Benefits Of Cbd Oil royal cbd oil users group because of what happened just now He was extremely fast and ran into the lobby in the blink of an eye.

But even so, there would still be one incident every day.

Some paper dolls and objects. If the paper figurine s wife royal cbd oil users group does marijuana help prevent seizures is sneaky and occupies a body that has accumulated the merits of Yin royal cbd oil users group Wishes, she will undoubtedly be better able to hide from the eyes of the Suppressing Demon and the Monk Dao, and will be able to live better.

The hanging guest took the group of bandits Sandy Beach Hotel royal cbd oil users group and evil spirits royal cbd oil users group back to the place where the funeral procession was attacked, let the bandits and evil spirits carry the corpses here, and helped the old lady back to the coffin, and then ordered the bandits and evil spirits to beat cbd benzo withdrawal the white flags.

Kill ah The night watchman standing next to the wine jar, catching royal cbd oil users group his eyeballs, .

ancient nutrition cbd oil

was the first to strike.

In case Zheng Tu still refuses to explain, then only by finding the royal cbd oil users group secret room can we find more pure science lab cbd oil clues and evidence, and find out the reason why Zheng Tu committed such maddening and dehumanizing crimes.

Ye Zhiqiu tried his best, but only got a beating.

You can rest well in the Demon Suppression Division and take command.

At the same time, we asked people who have contacts with Huang San, and they all said that he is a good man, and no one can be blamed, and e cloud royal cbd vape oil we have never seen him get angry with anyone.

Of course, these are all speculations by Qin Best Cbd Brand royal cbd oil users group Shaoyou based on clues in Zheng Tu s memory.

So the grandfather gave me the snake general Benefits Of Cbd Oil royal cbd oil users group order, but he actually left a mouth beside me.

But Qin Shaoyou did not continue to praise him, but glanced at Zhu Xiucai next to him.

So much so that royal cbd oil users group when the demons in Mianyuan County were swept away and Qiurong stopped beating drums every night, many residents felt unaccustomed and came to the town to ask royal cbd oil users group Cbd Manufacturing for Qiurong, regardless of whether there was a demon or not.

It s just that even if he used illusion to turn himself into a demon, Senior royal cbd oil and dementia Online Sale Brother Cui still didn t get rid of his instinct of pretending to be forceful.

Su Ting said this. rain. While she was talking, she undid the royal cbd oil users group Cbd Manufacturing wooden box she was carrying and took out the dissection saw.

Seeing everyone looking at him, Cui Youkui explained, I just noticed that the yin qi on the side of the earth vein was fluctuating.

But there are also some powerful Gu worms Benefits Of Cbd Oil royal cbd oil users group that penetrated Zheng Tu s suffocating aura and got into his body.

The ugly arm holding the knife suddenly royal cbd oil users group changed, revealing a person.

It seems that this temple blessing is really related to hanged guests, otherwise they would not be so hated by hanged ghosts, I almost thought I was myself.

The helpless royal cbd oil users group Senior Brother royal cbd oil users group Cui could only hide his embarrassment with a dry smile.

When Qin Shao said this, he stepped forward to check and made sure that there were no cracks on the cbd oil extra strength pillars.

In fact, in this world, the walls of most cities and towns are equipped with organs and magic circles to guard against evil spirits.

In addition to eradicating the remaining demons Sandy Beach Hotel royal cbd oil users group in the city, royal cbd oil and dementia Online Sale Qin Shaoyou also invited two Taoist priests, Tu Huang and Zeng Cong, to help repair the damaged city wall in Mianyuan County.

For the sudden appearance of Qiu Rong, let alone Qin Shaoyou unaware, even the night watchmen who followed him couldn t tell when and how Qiu Rong appeared.

He is an official, not an ordinary warrior.

It was able royal cbd oil users group to release these golden light chain seals and royal cbd oil users group suppress Zheng Tu s suffocating Best Cbd Brand royal cbd oil users group aura, and it had already tried royal cbd oil users group its best to release all the spiritual power that had been absorbed by eating ghosts royal cbd oil users group .

cbd oil and omeprazole

and spirits these days.

Qiu Shi was greatly surprised, and hurriedly wanted to taste the taste, only to find that he accidentally swallowed a bowl of looking up at the starry sky and swallowed it whole.

Before Mu Lao could react, the light of the fire cut off his long thorny royal cbd oil users group tongue with a swish.

Then he pushed the pot on Wu Bufan s head again It s all Wu Thief s orders, and royal cbd oil users group Cbd Manufacturing we are also forced to be helpless.

Immediately royal cbd oil users group after. Boom The devil suppressing hammer, like a blood soaked black dragon, smashed heavily on the black royal cbd oil users group Cbd Manufacturing lotus Buddha statue with its bloody energy.

Qin Shaoyou was also very royal cbd oil users group satisfied with this royal cbd oil users group new dish.

The royal cbd oil and dementia reports of Zhu Xiucai, Cui Youkui and Cbd Missouri royal cbd oil and dementia others also proved canada cbd gummies that the cbd popularity public security in Mianyuan County is recovering rapidly.

The words in the scroll are all vigorous and powerful, and just by looking at it, you can feel a sense of righteousness coming towards your face.

See also  CBD Gummies Taste Bad

Countless branches trembled, and large locust leaves fell like raindrops, swept towards Qin Shaoyou with the momentum of thunder.

It was his internal organs singing. Sandy Beach Hotel royal cbd oil users group It was his meridians and blood vessels whispering.

Qin Shaoyou stepped forward and glanced at it.

Qin Shaoyou originally planned to hand over Hong Xunyou to Zhu Xiucai to deal with, but when the royal cbd oil users group words came to his mouth, he suddenly had a new idea.

But the words cbd oil for arthritis reviews of Cui Youkui and Zhu Xiucai around him Benefits Of Cbd Oil royal cbd oil users group made him change his mind.

If we don t run away and pretend to be pilgrims, even if we hide with the hidden qi talisman Breath, as long as there are pine and cypress branches and other objects on the body, it will arouse the vigilance of the crane.

This is the reincarnation of heaven, good and evil are rewarded Seeing that it Sandy Beach Hotel royal cbd oil users group was useless to struggle and beg for mercy, a few wrestlers wanted to refuse when Zhu Xiucai asked for his name.

A piece of skin was sewn on the royal cbd oil users group area where the three acupoints of Xinxing, Shentang and Shendao on Feng Biao s back were located.

In the end, it was only with the help of this group of baby ghosts that the powerful warriors and monks were killed.

Then the topic turned to Zheng Tu s case. After talking about the case, he said to Daochang Tu Huang Senior Tu Huang, I heard from Senior Brother Cui that royal cbd oil users group you have done a lot of research on the magic circle, royal cbd oil users group and I wonder if you can help us go to the butcher shop to see if there is any cloth there.

That s life purchasing silver transformed by the evil spirits of the ghost He shook his head and said, You guys picked up the silver royal cbd oil users group Cbd Manufacturing ingots I didn t Benefits Of Cbd Oil royal cbd oil users group think about it.

Zhu Xiucai, royal cbd oil users group Cui Youkui and other relatively powerful people, and the ghostly aura emanating from it, probably estimated its strength.

Qin Shaoyou listened to the brows. Straight wrinkled.

And that Zhu Xiucai, I am afraid he also has experience in this area.

Unexpectedly, it was a big surprise for him It seems that buddy, I will be leaving Sandy Beach Hotel royal cbd oil users group Africa and joining the European Union from now on At the same time, Qin Shaoyou was a little fortunate, but fortunately he didn t promise to open more new dishes, otherwise he would be embarrassed now.

However, royal cbd oil users group the frontier troops they served were not the same, nor were they in the same defense cbd oil cancer research area, so they did not know each other.

However, I have observed that best cbd websites I can set up a formation around this area to temporarily suppress the yin qi gushing out of the well, and then royal cbd oil users group seal the qi eye after we have exterminated the ghost.

He wants to deal with Zheng Tu with all his strength, and doesn Cbd Missouri royal cbd oil and dementia t want to waste his blood here.

Just by looking at the name of the dish, you can tell that this is the main ingredient of the royal cbd oil users group rich woman s happy tongue that hangs down to her waist.

Confucian culture and righteousness. This Shangshu , together with looking up at the starry sky just royal cbd oil users group after eating, made Zhu Xiucai improve in .

nutiva hemp oil cbd

Confucianism and Taoism.

It s just that on equipment improvement, Zeng Cong made a suggestion.

Actually, jelly cbd gummies more coumadin and cbd oil and thc than ten years have passed since the royal cbd oil users group matter of Zhang Xingzu.

This made Qin Shaoyou a little worried, not Best Cbd Brand royal cbd oil users group knowing how Senior Brother Cui royal cbd oil and dementia Online Sale would be beaten.

Mu Lao didn t royal cbd oil users group think much Benefits Of Cbd Oil royal cbd oil users group about it. He saw that his ghost and zombies were already in place, so he gave an order Go Kill him Best Cbd Brand royal cbd oil users group Nearly a hundred zombies and ghosts rushed towards Cui Yougui from all directions In an instant, the ghost energy was overwhelming the sky, and the corpse energy was everywhere, and the world of Yizhuang seemed to have become a ghost.

For the rest, Qin Shaoyou doesn t need to worry about it.

With the improvement of royal cbd oil users group the talent royal cbd oil users group of Bright Eyes , Qin Shaoyou did see many things that he could not see or pay attention to before.

Fortunately, royal cbd oil users group he quickly heard that it was Qin Shaoyou royal cbd oil and dementia s voice, and just resisted the urge to do it.

CBD: A User’s Guide

CBD is seemingly everywhere and in everything, from CBD-infused creams to CBD-infused oils, tinctures, gummies, juices, and lollipops. But does it work, and is it safe? We’ve got your questions covered.

I n case you haven’t heard, CBD is a cure for whatever ails you, from insomnia and inflammation to pandemic angst. Or at least that’s what retailers, supermarkets, mini-marts, beauty stores, and coffee and smoothie shops across America would have you believe. There are CBD-infused creams. CBD-infused oils. CBD-infused tinctures, gummies, juices, lollipops, lattes, nutritional supplements, and even a CBD oil–infused pillow! What’s next, CBD-infused tampons? (Actually, that already exists. Really.)

According to the Brightfield Group, a market research firm, CBD sales were estimated to exceed $4 billion at the end of 2021, and by 2025, the industry’s total market value could reach a whopping $16 billion.

Put that in your pipe and smoke it.

But does CBD work?

That’s a question worthy of a Talmudic scholar, because the CBD world is complicated.

Some believe that it may have an important role to play in certain health outcomes.

Raphael Mechoulam, PhD, a professor of medicinal chemistry at Hebrew University in Jerusalem, Israel, has been studying the health benefits of cannabis and CBD since the early 1960s. Long considered the grandfather of cannabis research, Dr. Mechoulam and his team developed a process for synthesizing certain acids found in the cannabis plant. These acids — otherwise known as cannabidiolic acid (CBDA), and a methylated version of CBDA (CBDA-ME) — have been since studied for a variety of purposes, and might ultimately be used to develop new drugs for everything from arthritis and anxiety to inflammatory bowel disease and psoriasis.

Others believe CBD is unproven and risky.

The U.S. Food and Drug Administration (FDA) continues to investigate its potential harms, noting that while it recognizes the potential opportunity that cannabis-derived compounds (like CBD) can offer, it remains concerned about CBD products being marketed as supplements. (According to the FDA, THC and CBD products do not fit the definition of a dietary supplement.)

“FDA is aware that some companies are marketing products containing cannabis and cannabis-derived compounds in ways that violate the Federal Food, Drug, and Cosmetic Act (FD&C Act), and that may put the health and safety of consumers at risk,” the Agency wrote in its 2021 update, noting that it’s illegal to market CBD by adding it to a food or labeling it as a dietary supplement.

Among a number of problems with CBD, the FDA says, is that it can cause liver damage and diarrhea, it may impact the metabolism of other drugs, and it may cause male reproductive toxicity in humans, as has been found in animal studies.

Still, many consumers continue to believe CBD’s potential benefits. A report (PDF), also from the Brightfield Group, that analyzed 2,400 members of an online community of medical cannabis users found that 59 percent of CBD users say they use it for insomnia and 66 percent for anxiety, while 44 percent have taken it for depression and 49 percent for joint pain and inflammation.

With so much CBD noise out there, we’re feeling a little overwhelmed and confused about CBD. We want to know the real deal. For starters, is CBD the same as cannabis? Should we spend our hard-earned money on the stuff, or is it a scam? Is there any science to back up the claims that CBD is helping people sleep better, feel better, look better, or be an all-around better human? If so, is that in the form of CBD oil, tinctures, lotions, or should we vape it? But wait — isn’t vaping bad for you?

Relax. We’ve got you covered. Herewith, the real scoop on CBD. (Buyer beware: Abbreviations ensue.)

Common Questions & Answers

Endocannabinoids are molecules produced by the body to maintain homeostasis — stability — in response to changes in the environment. The endocannabinoid system interacts with all of the major systems and organs in the body to enable and restore optimal functioning.

The word “cannabinoid” usually refers to a chemical found in the cannabis (marijuana or hemp) plant. “Endo,” in this context, refers to substances produced inside the body. Endocannabinoids are, in effect, the body’s own source of cannabis-like substances.

See also  Can You Bring CBD Gummies To Hawaii

CBD and THC are plant cannabinoids, which operate much as endocannabinoids do, by attaching to certain receptors on the outsides of cells and altering the behavior of those cells or the bodily systems they are a part of.

Cannabinoids and endocannabinoids can affect pain perception, memory, mood, appetite, and many other bodily systems. The endocannabinoid system regulates the release of other neurotransmitters — that’s how it maintains homeostasis — and helps the body heal from any damage it sustains. Plant cannabinoids can similarly enhance feelings of well-being, but they can have undesirable side effects as well, particularly in young people.

Research suggests that endocannabinoids can be boosted by certain foods, such as those containing essential fatty acids, chocolate, herbs, spices, and teas, as well as by stress-reducing activities.

CBD: The Good, the Bad, and the Confusing

Before we get too much into the, er, weeds, it’s important to understand what CBD is and where it comes from.

Cannabis refers to a group of three varieties of marijuana plants with psychoactive properties: Cannabis sativa, Cannabis indica, and Cannabis ruderalis.

Cannabis contains more than 400 compounds, known as cannabinoids (pronounced keh-NAB-eh-noyd). The most well-known and researched are cannabidiol (CBD), and delta-9-tetrahydrocannabidiol (THC). Other lesser known components — THCA, CBN, CBC, and CBG — play different roles and have different effects in the body. (See our CBD glossary for details.)

The component in cannabis that is linked to its intoxicating effects (in other words, the “high,”) is THC. Conversely, CBD won’t get you high. Depending on your goals, this is either a good or a bad thing.

“Hemp” (which incidentally, is considered part of the CBD family) refers to non-intoxicating varieties that are high fiber or high seed-yielding and often used for rope, clothing, or sails. (Cocktail party fact: “The word ‘canvas’ comes from ‘cannabis,’ as it was made from cannabis fiber varietals,” says Will Kleidon, the CEO of Ojai Energetics in Ojai, California..)

In the United States, the legal definition of hemp is any cannabis plant whose delta-9 THC is below 0.3 percent.

What’s the Endocannabinoid System and How Does It Work?

The endocannabinoid system (ECS) is a biological system first described in the 1990s, and it plays a big role in brain, endocrine, and immune function. Its main role, however, is to maintain homeostasis, the internal biological balancing mechanism of the brain and body.

Two main elements of the system are endocannabinoid receptors, classified as CB1 and CB2. The body makes its own cannabinoids, known as endocannabinoids, that can act upon these receptors. But other varieties of cannabinoids, such as CBD, can interact with them, too.

What Are Cannabinoid Receptors?

Cannabinoid receptors are laced throughout the body, brain, and nerves.

  • Cannabinoid 1 (CB1) Receptors Most of these are in the central nervous system, especially neurons (nerve cells) in the brain.
  • Cannabinoid 2 (CB2) Receptors These are located mainly on immune cells but are also found in the central nervous system.

Both receptor types are activated by cannabinoids, which can be generated naturally inside the body (known as endocannabinoids) or can be introduced through a form of cannabis.

What’s the ‘Entourage Effect’?

The entourage effect refers to a theory that the whole is more effective than each part — or that the various compounds of the cannabis plant work best synergistically.

“It’s the theory that the cannabinoids, flavonoids, terpenes, and fatty acids all work together like an orchestra, in which all the instruments complement each other so you get the maximum effect of the plant,” says the cannabis researcher Monica Taing, PharmD. “CBD by itself can be a pain reliever, and THC can be a pain reliever by itself, but when combined, they work better for pain relief. That’s the entourage or ensemble effect.”

Now that that’s out of the way, let’s get into the nitty-gritty.

What Are the Legal Implications of Using CBD?

The legality of CBD is confusing.

In 2018, the Agriculture Improvement Act of 2018 (aka that year’s Farm Bill), legalized CBD derived from hemp — with the important caveat that it could only contain 0.3 percent of THC by dry weight, to be grown legally. This type of CBD is legal in 47 U.S. states with some restrictions, but totally illegal in Idaho, South Dakota, and Mississippi. Plants with more than 0.3 percent of THC are considered marijuana, which is legal for recreational use in 19 states, Washington, DC, and Guam.

Despite state laws legalizing the sale of cannabis for recreational or medicinal use, the Drug Enforcement Administration (DEA) (PDF) still classifies it as a Schedule 1 drug: “substances or chemicals [that] are defined as drugs with no currently accepted medical use and a high potential for abuse.” So, while marijuana is illegal on a federal level, states have different laws regarding marijuana and CBD.

Only one cannabis-derived drug product has been FDA approved: cannabidiol sold under the brand name Epidiolex, which contains a purified form of high-dose CBD to treat a rare, hard-to-treat form of epilepsy in children ages 1 and up.

How Do I Find Safe CBD Products? How Do I Know What I’m Getting?

Short answer: You often don’t.

The situation is not unlike that of dietary supplements, except for in the case of supplements, the FDA has defined a very clear set of restrictions — and the Federal Trade Commission, strict reinforcement of health claims. While the FDA has sent warning letters to certain companies selling CBD products, many products slip under the radar. In addition, state and Federal CBD regulations are at odds, so oversight can be difficult. What’s more, every state where medical or recreational marijuana is legal has its own testing rules and regulations, so something that passes muster in Massachusetts might not in California.

People often buy their products online or at the local drugstore or gas station, meaning that they often don’t know what they’re getting.

“Some CBD products don’t contain CBD, but they contain THC and heavy metals, so we need strong regulations,” says Dr. Taing. Indeed, as of May 21, 2022, poison control centers have managed 2,652 cases related to CBD, per the American Association of Poison Control Centers.

Some people have failed drug tests because they’ve unwittingly taken THC that was in a product that was supposed to contain only CBD. A study published in the Journal of the American Medical Association (JAMA) in November 2017 found that 21 percent of CBD products derived from hemp and sold online contained THC, even though THC wasn’t listed on the packaging.

A more recent study in JAMA Psychiatry showed that even a high-quality, high-potency cannabidiol product labeled as carrying as much as tenfold less than the legal limits of THC permissible under law might still result in positive urine drug tests.

Findings from another study, published June 2022 in the Journal of Cannabis Research, showed that of the 80 products evaluated, 37 contained CBD concentrations that were at least 10 percent higher or lower than the concentration listed on the label: 12 products contained less than 90 of what was listed, while 25 products contained more than 110 percent.

Even more worrisome, a study published in January 2019 in Forensic Science International examined nine liquids that were advertised as 100 percent natural CBD extract and found they contained potentially problematic compounds. One contained dextromethorphan, which is used in over-the-counter cough medication and is considered addictive when abused. Four others had a synthetic cannabinoid that can cause, among other things, anxiety, psychosis, and even death.

“As with any other product you would ingest, you have to be smart,” says Jahan Marcu, PhD, the editor in chief of the American Journal of Endocannabinoid Medicine, and the cofounder and chief science officer at the International Research Center on Cannabis and Mental Health.

What’s more, he says, every product should have a certificate of analysis, or COA — a document generated by a laboratory certifying its legitimacy and also listing the ingredients.

The Mayo Clinic uses the following checklist to identify high-quality products, as described in a 2019 issue of Mayo Clinic Proceedings:

  1. Does it meet the following quality standards? These include Current Good Manufacturing Practices (CGMP) certification from the FDA; European Union (EU), Australian (AUS), or Canadian (CFIA) organic certification; National Science Foundation (NSF) International certification.
  2. Does the company have an independent adverse event reporting program?
  3. Is the product certified organic or eco-farmed?
  4. Have their products been laboratory tested by batch to confirm tetrahydrocannabinol levels below 0.3 percent and no pesticides or heavy metals?

For more information, Project CBD, Certified Kind, Clean Green, and WeedMaps offer information on dispensaries, cannabis products, and brands.

Does It Matter if the CBD Is Organic?

In theory, yes, because without an organic label, there’s a potential for ingesting pesticides and chemical fertilizers. If you have a COA, then you’ll know what’s in the product.

But here’s the rub: Organic products are regulated by the U.S. Department of Agriculture (USDA), which is a federal agency. Since cannabis is considered a Schedule 1 drug, technically, medical cannabis couldn’t be designated as “organic,” unless it’s made from hemp.

In May 2018, Palmetto Grow became the first company to have USDA Organic certification for hemp flower and seed. Since then, other organic growers have joined the market. You can find a list of some of the best organic CBD products from EcoWatch and The Honest Consumer.

How useful was this post?

Click on a star to rate it!

Average rating 3 / 5. Vote count: 1

No votes so far! Be the first to rate this post.