Is CBD good for the brain? What about your dog's brain? Learn how CBD can be a natural neuroprotectant option for your pet. The recent surge in the sales of Cannabidiol-based products results from its wide availability. In the past couple of years, the market has almost increased to double its size. At the same time, the number of online stores selling CBD-based products has increased. Initially, when they came into the market, many had the
The Dog Brain: CBD as a Neuroprotectant
The brain is extremely complex. Even after centuries of study, there is still a significant amount of information to learn and many scientific discoveries to come. According to Surgical Neurology International , “ numerous physical, psychological, and emotional benefits have been attributed to marijuana since its first reported use in 2,600 BC in a Chinese pharmacopeia. The phytocannabinoids, cannabidiol (CBD), and delta-9-tetrahydrocannabinol (Δ9-THC) are the most studied extracts from cannabis sativa subspecies hemp and marijuana.”
One of the methods by which scientists study the brain is by introducing it to new materials. In this case; cannabis . One of the most researched study areas involves how cannabis impacts or affects the brain. A recent advance in science indicates CBD could possess neuroprotective properties (the ability to protect the brain in cases of illness and/or injury) .
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THC Versus Cannabis
THC is the most notorious constituent of the cannabis plant due to its psychoactive properties. When the cannabis plant is consumed or more specifically, when it is smoked, the THC (tetrahydrocannabinol) moves from the lungs into the bloodstream. The blood carries the compound from the lungs to the brain resulting in the ‘high’ sensation.
CBD, or Cannabidiol, is much different than THC in this aspect. That’s part of the reason the shift in research is moving from THC to CBD. In this shift, the medicinal uses for cannabis have expanded exponentially . CBD still interacts with the brain, but with different receptors, also resulting in a therapeutic effect .
CBD as a Neuroprotectant
Recent research findings show CBD may possess neuroprotective properties ; properties that prevent the breakdown of the central nervous system. Of course, more studies are needed to confirm this hypothesis, but we have a solid foundation to begin with.
As early as 1980, Cunha et al . , reported anticonvulsant benefits in 7 out of 8 subjects with medically uncontrolled epilepsy using marijuana extracts in a phase I clinical trial. Now, we are seeing results in patients with the following conditions :
- Multiple sclerosis
- Lennox-Gastaut/Dravet Seizures
The hippocampus, the portion of the brain that controls memory and emotional response, as well as the cerebellum, has been found to have higher CB1 receptor densities . In addition to memory and emotional response, these portions of the brain are also responsible for pain and movement. THC and other cannabinoids have been found to reduce symptoms and produce positive responses i n studies involving chronic pain.
In a study published in the Journal of Neurochemistry , scientists studied cultured microglial cells (cells that maintain the health of the central nervous system). These cells interact with others to create an inflammatory response when necessary and have been shown to be associated with CB2 receptors. Research suggests CB2 receptors play a critical role in inflammation; and, activation of CB2 receptors has been found in neurodegenerative diseases . Increased levels of activated CB2 receptors have also been found in mice with Alzheimer’s. These findings indicate that CB2 receptors may be useful when diagnosing neuroinflammation in the early stages of disease.
CBD, Endocannabinoid Receptors, and Neuroprotection
Due to the interaction among CB1 and CB2 receptors in neurodegenerative ailments, CBD may reduce inflammatory responses in neurodegenerative conditions. The way CBD interacts with CB2 receptors is one of the pathways found for CBD to serve as a neuroprotectant.
CBD targets cannabinoid and non-cannabinoid receptors, as well as enzymes, cellular uptake proteins, and transporters. According to Surgical Neurology Internationa l, “in animal models, CBD has demonstrated an ability to attenuate brain damage associated with neurodegenerative and/or ischemic conditions outside the ECS . CBD appears to stimulate synaptic plasticity and facilitates neurogenesis which may explain its positive effects on attenuating psychotic, anxiety, and depressive behaviors. The mechanisms underlying these effects involve multiple cellular targets to elevate brain-derived neurotropic factor (BDNF) levels, reduce microglia activation, and decrease levels of proinflammatory mediators .” Essentially, this is scientifically stating that CBD can significantly improve neurodegenerative symptoms by developing new neurons in the brain and increasing levels of communication among cells.
Research in both animals and humans has indicated numerous therapeutic benefits for brain function and brain protection due to direct effects on the endocannabinoid system and influence on endogenous cannabinoids . According to researchers, CBD shows promise as an anxiolytic, neuroprotective anti-inflammatory, antidepressant, and immunomodulator.
Traumatic brain injuries have also been under investigation in regard to CBD. Studies support the role of cannabinoids (CBD) and the interaction with endocannabinoid receptors , CB1 and CB2, in repair mechanisms. Studies in animals have shown administration of CBD post-injury reduces short-term brain damage by improving activity in the brain, reducing swelling, and preventing/shortening seizures . These are thought to be improved due to CBD’s ability to produce increased levels of anandamide (an endogenous endocannabinoid– found in a mammal’s endocannabinoid system ).
Legislation hasn’t quite caught up to the available research, but there are promising results indicating CBD may be used as a neuroprotectant in many cases . An increase in documented health benefits, like neuroprotection, must be made aware through public awareness and education . Since there is not much taught regarding cannabis medicine in medical or veterinary school, veterinarians and physicians alike are hesitant to view this as an alternative or supplement to any regimen. An increase in public education, and medical education, is key in advancing the future application of cannabis in veterinary and human practice.
Can CBD Ease Dogs with Neuropathic Pain?
The recent surge in the sales of Cannabidiol-based products results from its wide availability. In the past couple of years, the market has almost increased to double its size. At the same time, the number of online stores selling CBD-based products has increased. Initially, when they came into the market, many had their doubts about the products. With time, the doubts have vanished as the product range has proven reliable.
The sales have increased to a triple in the last couple of years, particularly in the United States of America. Several states which had earlier imposed a ban on the product have now legalized the distribution and production of Cannabidiol-Based products.
One more trait associated with these products is their inclusivity, as they are helpful for humans and animals as well. They are easy to consume and often work quickly. CBD Oil is particularly popular in pets as they take it through a dropper, which helps and controls the dose.
It can treat many common diseases in animals ranging from anxiety, restlessness, and neuropathic pain. Many specialists recommend consulting a specialist before starting with a dose plan.
WHAT IS NEUROPATHIC PAIN?
Everything in a multicellular organism’s body connects through the nervous system, which transfers and signals pain, anxiety, and every other feeling to the brain. Ever wondered why you take your hand off instantly after touching a hot object? The nerves from your fingers move the sensation to the brain and help the body to react.
The above case is the same for all mammals, same for domesticated pets like dogs. Several painful sensations get transferred through the neural network and notify the brain. It can often trigger a painful response when a particular part comes under physical stress. It also can trigger a seizure-like mental response in many dogs and other animals.
Vets claim that these problems are often a result of severe physical impact on the pet’s body. A hard blow around the spinal cord causes neuropathic pain in most cases. The neural networks go through the animal’s spinal cord and signal the feeling of pain in dogs.
WHAT IS CBD?
CBD or Cannabidiol originates from the leaves of the famous Sativa Plant. It is organic, which makes it popular among the consumer base. Food and Drug Administration has approved CBD because of the low content of THC. It contains 0.3% Tetrahydrocannabinol (THC) which makes it legal in most parts of the world. The fact that CBD is legal makes it more popular among the consumer base of the United States of America. Many clinical trials show that Cannabidiol-based products do not make the consumer come under any influence.
Cannabidiol-Based products are available in a wide variety, and some of the famous examples include CBD Oil, CBD Capsules, CBD Tincture, CBD Gummies, and many more. Cannabidiol Oil is very popular among pet owners, as it is liquid. It is easy to consume and often sweet, making it the perfect medicine for your furry friends.
Several pet owners have quickly adopted CBD products for their dogs, giving quick results.
HOW CAN CBD HELP?
Cannabidiol-based products have hemp extract, which is the primary constituent. The hemp extract originates from the leaves of the Sativa Plant and is pure. It mixes with the blood in the veins of the consumer and slows down the metabolism of your dog. As several diseases originate from irregular blood flow in the system, hemp extract is an effective tool. As Cannabidiol-based products are organic, they do not cause any short/long-term side effects on your pet dog.
The big problem with the old chemical-based drugs as they were notorious for causing side effects in many animals. Several times the chemical constituents may cause several skin-related diseases and allergies in your dogs. CBD for dogs solves the problem as it hardly ever causes any side effects on animals and humans.
When mixed with the bloodstream, the hemp extract causes an instant relief. It reduces the stress and restlessness of the animals, which provides long-term relief. CBD Oil drops onto the affected body part of the dog, which efficiently decreases the physical pain.
HOW DO DOGS CONSUME CBD?
The most popular among the wide range of CBD-Based products is CBD Oil due to its wide availability and efficiency. This oil often comes with a dripper on the edge of the bottle. This dripper makes sure that the required number of drops only goes inside the dog’s body. Many vets claim that an effective dose plan is essential to maximize the effectiveness of CBD Oil.
The affected body part in the animal, which causes a painful reflex, can be treated with oil drops. These drops reduce the inflammation in the affected area and help your dog relax gradually.
CBD ALSO HELPS IN OTHER DOG-RELATED PROBLEMS
Cannabidiol-Based products are popular among pet owners because of their multipurpose nature. They can be handy in operating neuropathic pain and treat other dog-related diseases.
- Many pets suffer from restlessness due to the busy work schedules of their owners. It can lead to physical stress and often lead to much unused energy, which can be very harmful to your pets. CBD-Based products can calm down the stressed nerves in the dogs and make them relax.
- The ever-increasing pollution and chemical ingredients in our everyday consumables can cause severe problems in dogs. Many pet parents complain that the allergies in their dogs have also increased with time. CBD Oil is beneficial in treating skin allergies and the severity of it. It kills the germs and reduces the inflammation caused in open wounds.
- Digestion problems in pets are a common trend, especially in domesticated dogs. The hemp extract in CBD reduces the inflammation in the stomach and helps with digestion. It often takes a week or two to observe the oil’s effectiveness. Try CBD hemp oil for pets and your best friend will love you.
CBD-Based products are new in the market, attracting much stigma around them. Once the user manages to get over them and starts to use these products, the benefits, and the results are quickly visible. Various clinical trials conducted across the United States of America show that Cannabidiol-Based products hardly cause any short/long-term side effects.
Many states that earlier had banned CBD-Based products have started to uplift the ban. Governments across most states in the USA are promoting Cannabidiol-Based products. It has made CBD an effective alternative over chemical drugs for pets as it is organic.