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“Subjective effects are due to THC causing different patterns of functional connectivity in the brain… a measure of how much they talk to each other,” said Nick Jikomes, Leafly’s Director of Science & Innovation, and host of the Good Chemistry podcast.

Blue Dream is another legendary hybrid that people love for its relaxing qualities, morale-boosting euphoria, and overall feel-good high that brings a smile to your face. It’s a cross of Blueberry and Haze that produces a sweet, berry, terpene profile that’s dominant in myrcene, pinene, and caryophyllene.

Energized: Green Crack

OG Kush is the hybrid of all hybrids that swept California by storm in the 1990s and set the bar for many of the high-potency strains we smoke today. It has a flavor of earthy, sour, gassy, and skunky terpenes that we’ve come to identify as “kush,” which give way to an intense cerebral experience.

Though it can be extremely potent, OG Kush is still the perfect example of a long-lasting euphoric high that doesn’t much teeter toward feeling energizing or sleepy—you’ll just be stoned.

And with that, here are five of the best strains to set your dials to feeling energized, uplifted, euphoric, relaxed, or sleepy.

OG Kush is one of those strains that’s a banger without contest. When asked what strain they would pick if they could only smoke one for the rest of their lives, half our experts chose OG Kush. Pete Pietrangeli, the VP of Cosmic Distribution, responded immediately and without hesitation, “OG Kush. I don’t even have to think about it.”

To determine the best strains of all time as well as what makes a strain “great,” we spoke to some of the most knowledgeable experts in the weed industry and the growers behind the strains themselves.

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While the original cut lives up to the reputation that precedes it, the Sour Diesels of today vary greatly. “There’s a lot of faux Sours out there,” explained AJ. “But some of them are actually pretty good. Sometimes someone will give me a call and say, ‘yo, I think this is the original Sour.’ And I’ll get a cut and grow it out. It never is, but it’s still really good. When it comes down to it, there’s no real authentication process, and I can’t go around checking. So, who knows?”

Tangie

Chiah Rodriguez, the second-generation cultivator behind River Txai Farms, a Mendocino operation distributed by Arcanna Flowers, puts an equal emphasis on the flower’s smell transferring to the flavor of the smoke. When asked what makes a strain great, Rodriguez shared, “High terpenes and something that has a unique nose and kind of hits you in the face when you open the drawer.”

While there are numerous factors that contribute to a strain’s greatness, the defining characteristic of a great strain is the smell.

“The Sour Diesel was a bag seed that came from Chem Dawg in the mid-90s,” said AJ. “Some people, myself included, put it out there and made a lifestyle out of it . It just blew up and became a cultural icon.” He continued, “It was a specialty product because New York had a specialty market that allowed for that product to exist. It probably couldn’t have existed in many other places because there wouldn’t have been a market and opening in the market for something like that. It was a very expensive product compared to what else was around, and what was coming from Canada, California, and other places.”

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OG Kush was born in the late ’90s when a cut of Hindu Kush from Amsterdam was crossed with unknown genetics from Northern California. Gassy, skunky, and spicy as shit, OG Kush is a stellar strain with a heady, relaxing, and euphoric high. The cut went on to spur tons of famous West Coast strains, like Bubba Kush, GSC, and Headband and is considered hugely influential in shaping the strains we see coming out of the California weed market.

If you love cannabis it’s a safe bet you’re always on the hunt to find the best weed strain. We reviewed thousands of weed strains available on the market as of November 2020 and created a simple list to help you pick the most potent and strongest weed strain for your personal enjoyment and therapeutic pursuits. We evaluated each marijuana strain across a variety of factors including potency, effects, lineage, THC & CBD content, aroma, appearance, and more, and these are truly the best strains out there.

Read on below to see the list of the 10 best types of weed and the highest THC strains & highest CBD strains available.